Chlamydia and Gonorrhea Urinalysis

The PCR testing process can detect the presence of bacterial DNA, which could indicate that you have a Chlamydia or gonorrhea infection. This test is highly efficient in confirming the presence and identification of the causative agent.

Gonorrhea is a sexually transmitted infection caused by the bacterium N. gonorrhea. These bacteria often thrive in moist areas of the reproductive and urinary systems. But they can also grow in the eyes, mouth, throat, or anus.

Your healthcare worker will prescribe this test when he suspects symptoms like pain or burning during urination, swelling in the testicles or scrotum, an abnormal discharge from the anus, penis, or vagina, rectal pain, bleeding from the rectum, etc.

Direct urine polymerase chain reaction (PCR), with the view of implementing a simplified PCR strategy for high-throughput chlamydia and gonorrhea screening in remote settings. Briefly, a simple dilution of the urine was performed before adding it directly to a real-time PCR reaction. (1)

Figure 1: Urine PCR for Gonorrhea or Chlamydia infections (3)

 

 

Rapid and specific detection of the sexually transmitted pathogens Chlamydia trachomatis (C. trachomatis) and Neisseria gonorrhoeae (N. gonorrhoeae) would enable early treatment and management of their spread. (2)

Studies show that the simplified PCR strategy may be feasible for rapid screening and improving chlamydia and gonorrhea treatment in remote settings. (1)

Unprotected sex can lead to these infections, Antibiotics are used for treatment.

 

 

 

 

References:

  • Rahimi, F., Goire, N., Guy, R., Kaldor, J. M., Ward, J., Nissen, M. D., Sloots, T. P., & Whiley, D. M. (2013). Direct urine polymerase chain reaction for Chlamydia and gonorrhea: a simple means of bringing high-throughput rapid testing to remote settings?. Sexual health10(4), 299–304. https://doi.org/10.1071/SH12108
  • Yu, B., An, Y., Xu, G., & Shan, H. (2016). Detection of Chlamydia trachomatis and Neisseria gonorrhoeae based on cross-priming amplification. Letters in applied microbiology62(5), 399–403. https://doi.org/10.1111/lam.12560

image from https://www.sciencedirect.com/science/article/pii/S0167701220308198

Chlamydia and Gonorrhea Urinanalysis

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